Advanced Post Live
Meanwhile, Crystal Palace, many pundits' pick to break into the top eight, welcome league leaders Manchester City to the capital after raiding Stamford Bridge before the international break.
Newly-promoted duo Norwich City and Bournemouth lock horns at Carrow Road while Watford host high-flying Swansea City.
Before the big derby between Manchester United and Liverpool, which sees Louis van Gaal try and repair his reputation after a turbulent few weeks, Southampton also travel to West Brom hoping to improve on their unremarkable start.
Today's fixtures in full:
Everton 3 Chelsea 1 (12:45 BST)
Arsenal v Stoke
Crystal Palace v Man City
Norwich v Bournemouth
Watford v Swansea
West Brom v Southampton
Man Utd v Liverpool (17:30 BST)